Necessity to Measure PCBs and Organochlorine Pesticide Concentrations in Human Umbilical Cords for Fetal Exposure Assessment
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چکیده
منابع مشابه
Necessity to Measure PCBs and Organochlorine Pesticide Concentrations in Human Umbilical Cords for Fetal Exposure Assessment
Three types of tissue samples--umbilical cord (UC), umbilical cord serum (CS), and maternal serum (MS)--have often been used to assess fetal exposure to chemicals. In order to know the relationship of contamination between mothers and fetuses, we measured persistent chemicals in comparable sets of the three tissue samples. Also, we analyzed the association between the chemicals in maternal and ...
متن کاملRetrospectivein utero exposure assessment of PCBs using preserved umbilical cords and its application to case-control comparison.
OBJECTIVES The aim of this study is to assess preserved umbilical cords as chemical exposure media to investigatein utero chemical exposure. Furthermore, we aim to apply preserved umbilical cords to retrospective studies of the relationship betweenin utero chemical exposure and neurodevelopment disorders. METHODS Two sets of preserved umbilical cord samples were analyzed for exposure to polyc...
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BACKGROUND Declining human reproductive health over the last 60 years has been proposed to be due to effects of environmental chemicals, especially endocrine disrupting compounds, on fetal development. We investigated whether a model pesticide, dieldrin, at concentrations within both maternal circulation and environmental ranges (1 pmol/l = 0.0004 p.p.b. = 380.9 pg/l), could disrupt the human f...
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متن کاملAssociation of In Utero Organochlorine Pesticide Exposure and Fetal Growth and Length of Gestation in an Agricultural Population
From 1940 through the 1970s, organochlorine compounds were widely used as insecticides in the United States. Thereafter, their use was severely restricted after recognition of their persistence in the environment, their toxicity in animals, and their potential for endocrine disruption. Although substantial evidence exists for the fetal toxicity of organochlorines in animals, information on huma...
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ژورنال
عنوان ژورنال: Environmental Health Perspectives
سال: 2005
ISSN: 0091-6765,1552-9924
DOI: 10.1289/ehp.7330